2009/04/22

Ladder diabetes drug law

Divided into type 1 diabetes and type 2 diabetes, the vast majority (90%) for type 2 diabetes. Type 1 diabetes is due to the absolute lack of insulin caused by insulin treatment or to choose to take, such as islet transplantation can produce insulin, the body treatment. And type 2 diabetes is different, it factors in initiating the pathogenesis of insulin resistance may be, with the progress of the course, eventually accompanied by lack of insulin, when these two factors has developed to a certain degree of dominance on the occurrence of diabetes, the disease gradually increase, eventually leading to failure of insulin.

In general, diabetes is divided into four stages of the course. Genetic susceptibility that period, period of impaired glucose tolerance (pre-diabetes), diabetes period, advanced diabetes. The first two phases have not yet occurred as a result of diabetes, should take a preventive approach, including diet and exercise therapy and lifestyle changes. Period should be taken in diabetic diet, exercise, drugs, blood glucose monitoring and diabetes education in combination therapy, in which drug therapy should be de-escalation therapy safer and more effective, more convenient, more economical, can be the optimal treatment for diabetes treatment. The pathogenesis of diabetes therapy is the theoretical basis for the ladder, because with the progress of diabetes, insulin resistance and persistent increase of the functions so that decrease islet. Therefore, our response is as soon as possible on the one hand, the use of insulin sensitizers to reduce insulin resistance, on the other hand, to avoid the premature use of drugs to stimulate insulin secretion, islet function, as far as possible to protect and ensure the daily physiological demand for insulin. Its purpose is to control metabolic disorders, the prevention of complications. Specific programs are as follows: the first step in the use of specific or non-specific insulin sensitizer diabetes with diet, exercise therapy, such as access to the second program is invalid; the second step the use of insulin sensitizers with postprandial blood glucose regulators, such as Rogge and one child's cry or times acarbose or Novo Yan Lung, the third step is invalid and choose treatment options; the third step with insulin sensitizers increase postprandial blood glucose regulator, matched sulfonylurea hypoglycemic agents, invalid The fourth step to enter the treatment program; the fourth step, oral medication and insulin treatment, in accordance with the degree of insulin taken by the lack of insulin replacement therapy (day 1 or 2 times injection) or insulin replacement therapy (3 times a day to 4 times injection).

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